The Inventiveness of Nature: An Interview with Werner Arber
نویسنده
چکیده
I admit to having a soft spot for the bacterial phenomenon of host-specific modification and restriction. I vividly remember first learning about this mechanism to stave off marauding DNA as a beginning graduate student in the mid1970s. Preceding the discovery of its modern-day defensive counterpart, CRISPR (clustered regularly interspaced short palindromic repeats) by about 50 years, restriction and modification was not only a remarkable story in itself, but also spawned extremely useful technology. In past issues, I have interviewed Hamilton
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